ISBN: 3540657592
TITLE: Mechanisms of B Cell Neoplasia 1998 15th Workshop
AUTHOR: Melchers, Fritz; Potter, Michael (Eds.)
TOC:

List of Contributors. XIII
Speakers at the B Cell Neoplasia Workshop 1998 XVII
I B Cell and Plasma Cell Development
E. ten Boekel, T. Yamagami, J. Andersson, A.G. Rolink and F. Melchers
The Formation and Selection of Cells Expressing PreB Cell Receptors and B Cell Receptors 3
R. Ceredig, A.G. Rolink, F. Melchers and J. Andersson
Fetal Liver Organ Cultures as a Tool to Study Selection Processes During B Cell Development 11
M. Carroll
Negative Selection of Self-reactive B Lymphocytes Involves Complement 21
T.E.I. Taher, R. van de Voort, L. Smit, R.M.J. Keehnen, E.J.M. Schilder-Tol, M. Spaargaren and S.T. Pals
Cross-talk Between CD44 and c-Met in B Cells 31
A.G. Rolink, F. Melchers and J. Andersson
The Transition from Immature to Mature B Cells 39
F. Martin and J.F. Kearney
CD21^high IgM^high Splenic B Cells Enriched in the Marginal Zone: Distinct Phenotypes and Functions 45
K. Yang, M. Davila and G. Kelsoe
Do Germinal Centers Have a Role in the Generation of Lymphomas? 53
M. Carroll 
Role of Complement Receptors CD2l/CD35 in B Lymphocyte Activation and Survival 63
R.A. Manz, G. Cassese, A. Thiel and A. Radbruch
Long-lived Plasma Cells Survive Independent of Antigen 71
II Chemokines and Chemokine Receptors
V. Pevzner, I. Wolf, R. Burgstahler, R. Frster and M. Lipp
Regulation of Expression of Chemokine Receptor BLRl/CXCR5 during B Cell Maturation 79
J.G. Cyster, V.N. Ngo, E.H. Ekland, M.D. Gunn, J.D. Sedgwick and K.M. Ansel
Chemokines and B cell Homing to Follicles 87
C. Schaniel, F. Sallusto, P. Sideras, F. Melchers and A.G. Rolink
A Novel CC Chemokine ABCD-I, Produced by Dendritic Cells and Activated B Cells, Exclusively Attracts Activated T Lymphocytes 95
P. Ghia, C. Schaniel, A.G. Rolink, L.M. Nadler and A.A. Cardoso
Human Macrophage-Derived Chemokine (MDC) is Strongly Expressed Following Activation of both Normal and Malignant Precursor and Mature B Cells 103
C.S. Rabkin and S. Sei
Susceptibility Genes for AIDS and AIDS-Related Lymphoma 111
D. D'Ambrosio, P. Panina-Bordignon, L. Rogge and F. Sinigaglia
Molecular Mechanisms of T Helper Cell Differentiation and Tissue-specific Migration 117
F. Sallusto, B. Palermo, A. Hoy and A. Lanzavecchia
The Role of Chemokine Receptors in Directing Traffic of Naive, Type 1 and Type 2 T Cells 123
M.H. Grler, G. Bernhardt and M. Lipp
A Lymphoid Tissue-Specific Receptor, EDG6, with Potential Immune Modulatory Functions Mediated by Extracellular Lysophospholipids 131
III Chromosomal Translocations, DNA
Rearrangements and Somatic Hypermutations
U. Klein, K. Rajewsky and R. Kppers
Phenotypic and Molecular Characterization of Human Peripheral Blood B-Cell Subsets with Special Reference to N-Region Addition and Jkappa-Usage in VkappaJkappa-Joints and kappa/lambda-Ratios in Naive Versus Memory B-Cell Subsets to Identify Traces of Receptor Editing Processes 141
H. Jacobs, A. Puglisi, K. Rajewsky and Y. Fukita
Tuning Somatic Hypermutation by Transcription 149
G. Klein
Immunoglobulin Gene Associated Chromosomal Translocations in B Cell Derived Tumors 161
E. Hilgenfeld, H. Padilla-Nash, E. Schrck and T. Ried
Analysis of B-cell Neoplasias by Spectral Karyotyping (SKY) 169
A.E. Coleman, T. Ried and S. Janz
Recurrent Non-reciprocal Translocations of Chromosome 5 in Primary T ( 12; 15 )-positive BALB/c Plasmacytomas 175
J.F. Mushinski, J. Hanley-Hyde, G.J. Rainey, T.I. Kuschak, C. Taylor, M. Fluri, L.M. Stevens, D.W. Henderson and S. Mai
MYC-Induced Cyclin D2 Genomic Instability in Murine B Cell Neoplasms 183
R. Kppers, T. Goossens and U. Klein
The Role of Somatic Hypermutation in the Generation of Deletions and Duplications in Human lg V Region Genes and Chromosomal Translocations 193
J. Shaughnessy and B. Barlogie
Chromosome 13 Deletion in Myeloma 199
T. Szczepanski, M.J Pongers-Willemse, A.W. Langerak and J.J.M. van Dongen
Unusual Immunoglobulin and T-Cell Receptor Gene Rearrangement Patterns in Acute Lymphoblastic Leukemias 205
W.M. Aarts, R.J. Bende, S.T. Pals and C.J.M. van Noesel
Analysis of Variable Heavy and Light Chain Genes in Follicular Lymphomas of Different Heavy Chain Isotype 217
E.-E. Schneider, T. Albert, D.A. Wolf and D. Eick
Regulation of c-myc and Immunoglobulin Kappa Gene Transcription by Promoter-proximal Pausing of RNA Polymerase II 225
IV Biology of Lynphomagenesis, B-CLL, Autoimmunity
C.S. Rabkin
Epidemiology of B-Cell Lymphomas 235
A. Alfarano, P. Circosta, A. Vallario, C. Camaschella,S. Indraccolo, A. Amadori and F. Caligaris-Cappio
Alternative Splicing of CD79a (Igalpha) and CD79b (Igbeta) Transcripts in Human B-CLL Cells 241
H.-C. Morse III, C.-F. Qi, L Tadesse-Heath, S.K. Chattopadhyay, J.M. Ward, A. Coleman, J.W. Hartley and T.N. Fredrickson
Novel Aspects of Murine B Cell Lymphomas 249
R. Dalla-Favera, A. Migliazza, C.-C. Chang, H. Niu, L. Pasqualucci, M. Butler, Q. Shen and G. Cattoretti
Molecular Pathogenesis of B Cell Malignancy: The Role of BCL-6 257
G. A. Rathbun, Y. Ziv, J.H. Lai, D. Hill, K.H. Abraham, Y. Shiloh and L.C. Cantley
ATM and Lymphoid Malignancies; Use of Oriented Peptide Libraries to Identify Novel Substrates of ATM Critical in Downstream Signaling Pathways 267
N. Ibnou-Zekri, T.J. Vyse, S.J. Rozzo, M. Iwamoto, T. Kobayakawa, B.L. Kotzin and S. Izui
MHC-linked Control of Murine SLE 275
B. Wollscheid, J. Wienands and M. Reth
The Adaptor Protein SLP-65/BLNK Controls the Calcium Response in Activated B Cells 283
K.A. Siminovitch, A.-M. Lamhonwah, A.-K. Somani, R. Cardiff and G.B Mills
Involvement of the SHP-I Tyrosine Phosphatase in Regulating B Lymphocyte Antigen Receptor Signaling, Proliferation and Transformation 291
R.C. Hsueh, A.K. Hammill, R. Marches, J.W. Uhr and R.H. Scheuermann
Antigen Receptor Signaling Induces Differential Tyrosine Kinase Activation and Population Stability in B-Cell Lymphoma 299
U. Gnthert
Importance of CD44 Variant Isoforms in Mouse Models for Inflammatory Bowel Disease 307
U. Zimber-Strobl, I. Strobl, H. Hfelmayr, B. Kempkes, M.S. Staege, G. Laux, B. Christoph, A. Polack and G.W. Bornkamm
EBNA2 and c-myc in B Cell Immortalization by Epstein-Barr Virus and in the Pathogenesis of Burkitt's Lymphoma 315
V Myeloma, Plasmacytomas and Related Subjects
K. Nilsson: P. Georgii-Hemming, H. Spets and H. Jernberg-Wiklund
The Control of Proliferation, Survival and Apoptosis in Human Multiple Myeloma Cells in vitro 325
B. Klein, X.Y. Li, Z.Y. Lu, M. Jourdan, K. Tarte, J. Brochier, E. Claret, J. Wijdenes and J.F. Rossi
Activation Molecules on Human Myeloma Cells 335
F.G.M. Kroese and N.A. Bos
Peritoneal B-l Cells Switch in vivo to IgA and these lgA Antibodies can hind to Bacteria of the Normal Intestinal Microflora 343
M. Potter and L. Kutkat
Inhibition of Pristane-Induced Peritoneal Plasmacytoma Formation 351
S. Zhang and B.A. Mock
The Role of rho 16^INK4a (Cdkn2a) in Mouse Plasma Cell Tumors 363
K. Felix, K. Kelliher, G.-W. Bornkamm and S. Janz
Transgenic Shuttle Vector Assays for Assessing Oxidative B-cell Mutagenesis in vivo 369
S. Silva and G. Klein
Plasmacytoma Induction in Specific Pathogen-Free (SPF) bcl-2 Transgenic BALB/c Mice 379
H.B. Richards, M. Satoh, V.M. Shaheen, H. Yoshida and W.H. Reeves
Induction of B Cell Autoimmunity by Pristane 387
O. Sagi-Assif, D. Douer and I.P. Witz
Cytokine Network Imbalances in Plasmacytoma-Regressor Mice 395
R.A. Vescio and J.R. Berenson
The Role of Human Herpesvirus-8, (HHV-8), in Multiple Myeloma Pathogenesis 403
Subject Index 411
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