ISBN: 3540671544
TITLE: The Peroxidase Multigene Family of Enzymes
AUTHOR: Petrides, Petro E.; Nauseef, William M. (Eds.)
TOC:

1 Peroxidases: A Historical Overview of Milestones in Research on Myeloperoxidase
Robert A. Clark 1
2 Targeting of Proteins to Lysosomes and Granules
Andrej Hasilik 11
3 Sorting and Processing of Neutrophil Granule Proteins
Urban Gullberg, Niklas Bengtsson, Elinor Blow, Daniel Garwicz, Anders Lindmark, Inge Olsson 22
4 X-Ray Crystallographic Studies of Human Myeloperoxidase
C.A. Davey, T Fiedler, R.E. Fenna 31
5 Structural and Biological Properties of Human Recombinant Myeloperoxidase
Nicole Moguilevsky, Alex Bollen 38
6 Recent Insights into the Biosynthesis and Processing of Human Myeloperoxidase
William M. Nauseef 45
7 Targets for Myeloperoxidase-Dependent Bactericidal Activity
Henry Rosen 52
8 Reactions of Myeloperoxidase and Production of Hypochlorous Acid in Neutrophil Phagosomes
Christine C. Winterbourn, Christine J. van Dalen, Mark B. Hampton, Anthony J. Kettle 58
9 Acquisition and Use of Myeloperoxidase in the Microbicidal Activity of Macrophages
Laszlo Marodi, Christopher Tourney, Rita Kaposzta, Richard B. Johnston Jr., Nicole Moguilevsky 68
10 Cooperative Interactions of the Peroxidase and Nitric Oxide Pathways in Inflammatory Oxidant Production
Jason P. Eiserich, Bruce A. Freeman, Carroll E. Cross, Albert van der Vliet 72
11 The Role of the Monoclonal Antibody Anti-Myeloperoxidase (anti-MPO) in the Diagnosis and Classification of Acute Leukaemias
Estella Matutes 86
12 The Role of Myeloperoxidase in Myeloid Leukemia and Multiple Sclerosis
Wanda F. Reynolds 93
13 Pathways for Oxidative Tissue Injury by Myeloperoxidase
Jay W. Heinecke 102
14 Myeloperoxidase Activity of Neutrophils in Cystic Fibrosis
Vronique Witko-Sarsat 107
15 Structure Function Relationships Amongst Members of the Animal Peroxidase Family of Proteins
Rosa Pia Ferrari, Silvio T raversa 114
16 Myeloperoxidase (MPO) and Eosinophil Peroxidase (EPO) Deficiency in the Region Friuli-Venezia Giulia of North-Eastern Italy
Pierluigi Patriarca, Maurizio Romano 122
17 Biochemistry and Physiology of Thyroid Peroxidase
Jan J.M. de Vijlder, Hennie Bikker 129
18 Severe Congenital Hypothyroidism Caused by Mutations in the Thyroid Peroxidase Gene
Hennie Bikker, Jan J.M. de Vijlder 133
19 Screening for Leukocyte Peroxidase Deficiencies by Means of Flow Cytometry: Application to the Study of Prevalence, Pathology and Genetics
Dolphe Kutter, Luc Verstraeten 136
20 Prevalence of Inherited Myeloperoxidase Deficiency in Japan
Kazuo Suzuki, Hiroyuki Nunoi, Makoto Miyazaki, Fumikazu Koi 145
21 Acquired and Inherited Forms of Myeloperoxidase Deficiency: Clinical and Hematological Features
Francesco Lanza, Angela Latorraca, Sabrina Moretti, Barbara Castagnari, Luisa Ferrari, Gianluigi Castoldi 150
22 Myeloperoxidase-Positive and Negative Granulocytes: Investigations by Flow Cytometry
Gernot Bruchelt, Claudia E. Gerber, Peter Bader, Matthias Zipfel, Thomas Klingebiel, Rupert Handgretinger, Dietrich Niethammer 157
23 Mutation Analysis for Genotype-Phenotype Relationships in Myeloperoxidase Deficiency
Petro E. Petrides, Susanne Bock, Chuanbing Zang 166
24 Diagnostic Significance of Antineutrophil Cytoplasmic Antibodies (ANCA) in Systemic Vasculitides
Loc Guillevin, Bernard Jarrousse 173
25 Immunodiagnostic Aspects of Autoantibodies Against Myeloperoxidase
Elena Csernok, Wolfgang L. Gross 180
26 Pathophysiological Mechanisms in Anti-Myeloperoxidase-Associated Vasculitis
Jan Willem Cohen T ervaert 186
Subject Index 191
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