ISBN: 3540669647
TITLE: Microreaction Technology: Industrial Prospects
AUTHOR: Ehrfeld, W. (Ed.)
TOC:

Author Index XV
Part 1
Opening Lectures
Process Intensification Through Miniaturization of Chemical and Thermal Systems in the 2lst Century 2
R.S. Wegeng, M. K. Drost, D.L. Brenchley
Implementation of Microreaction Technology in Process Engineering 14
W. Ehrfeld, V. Hessel, S. Kiesewalter, H. Lwe, Th. Richter, J. Schiewe
Part 2
Design and Production of Microreactor Systems
Lecture Session
Fabrication and Application of Silicon-based Microchannels 36
J.G.E. Gardeniers, R. W. Tjerkstra, A. van den Berg
Macroporous and Mesoporous Silicon: New Materials for Microfluidic and Microreaction Devices 45
V. Lehmann
The Effect of Shape Variation in Microlamination on the Performance of High-Aspect-Ratio, Metal Microchannel Arrays 53
B.K. Paul, R.B. Peterson, W. Wattanutchariya
Fabrication of Microchannel Chemical Reactors Using a Metal Lamination Process 62
D. W. Matson, P.M. Martin, D.C. Stewart, A. L. Y. Tonkovich, M. White, J.L. Zilka, G.L. Roberts
Microreactor Technology for Biological Applications 72
G.M. Greenway, T. McCreedy
Laserprocessing for Manufacturing Microfluidic Devices 80
E. Bremus, A. Gillner, D. Hellrung, H. Hcker, F. Legewie, R. Poprawe, M. Wehner, M. Wild
Functional Coatings for Microstructure Reactors and Heat Exchangers 90
M. Fichtner, W. Benzinger, K. Haas-Santo, R. Wunsch, K. Schubert
Polymer Nanowell Plates with Variable Well Slope Angles 102
H. Becker, T. Klotzbcher
Micro Molding of Fluidic Devices for Biochemical Applications 113
M. Niggemann, W. Ehrfeld, L. Weber
Part 3
Microreactors in Combinatorial Chemistry
Lecture Session
Combinatorial Organic Compound Libraries on Continuous Surfaces: Towards Chemical Chips 124
L. Germeroth, U. Reineke, K. Dietmeier, C. Piussek, N. Heine, D. Scharn, T. Ast, M. Schulz, H. Mutuschewski, A. Kramer, J. Schneider-Mergener, H. Wenschuh
Part 4
Microreactors in Production Processes
Lecture Session
Electrochemical Microreactors: A New Approach for Microreaction Technology 136
A. Ziogas, H. Lwe, M. Kpper, W. Ehrfeld
High Temperature HCN Generation in an Integrated Microreaction System 151
V. Hessel, W. Ehrfeld, K. Golbig, C. Hofmann, St. Jungwirth, H. Lwe, Th. Richter, M. Storz, A, Wolf, O. Wrz, J. Breysse
Micro Mixing Effects in Continuous Radical Polymerization 165
T. Bayer, D. Pysall, O. Wachsen
Novel Liquid Phase Microreactors for Safe Production of Hazardous
Specialty Chemicals 171
T.M. Floyd, M. W. Losey, S.L. Firebaugh, K. F. Jensen, M.A. Schmidt
Experiences with the Use of Microreactors in Organic Synthesis 181
H. Krummradt, U. Koop, J. Stoldt
A Microstructured Reactor for the Catalytic Partial Oxidation of Methane to 187
J. Mayer, M. Fichtner, D. Wolf, K. Schubert
Expansion of Microreactor Capabilities through Improved Thermal Management and Catalyst Deposition 197
A. J. Franz, S. K. Ajmera, S. L. Firebaugh, K. F. Jensen, M.A. Schmidt
Synthesis of Ethylene Oxide in a Microreaction System 207
H. Kestenbaum, A. Lunge de Oliveira, W. Schmidt, F. Schth, W. Ehrfeld, K. Gebauer, H. Lwe, Th. Richter
Selective Reactions in Microchannel Reactors 213
Kursawe, E. Dietzsch, S. Kah, D. Hnicke, M. Fichtner, K. Schubert, G. Wiemeier
Periodic Operation in Microchannel Reactors 224
M.A. Liauw, M. Baerns, R. Broucek, O.V. Buyevskaya, J.-M, Commenge, J.-P. Corriou, L. Falk, K. Gebauer, H.J. Hefter, O.-U. Langer, H. Lwe, M. Matlosz, A. Renken, A. Rouge, R. Schenk, N. Steinfeldt St. Walter
Poster Session
Micro-Reactor Synthesis: Synthesis of Cyanobiphenyls Using a Modified Suzuki Coupling of an Aryl Halide and Aryl Boronic Acid 235
V. Skelton, G.M. Greenway, S.J. Haswell, P. Styring, D.O. Morgan
Optimization of Reaction-Separation Networks via Mass Integration on the mu-Scale 243
F. tepank, M. Marek
Modelling of Gas-Liquid Catalytic Reactions in Microchannels 253
P. Angeli, D. Gobby, A. Gavriilidis
Simultaneous Screening of Catalysts in Microchannels: Methodology and Experimental Setup 260
T. Zech, D. Hnicke, A. Lohf, K. Golbig, Th. Richter
Palladium Membrane Microreactors 267
A.J. Franz, K.F. Jensen, M.A. Schmidt
A Micro Packed-Bed Reactor for Chemical Synthesis 277
M. W. Losey, M.A. Schmidt, K. F. Jensen
Parallel Synthesis and Testing of Heterogeneous Catalysts 287
U. Rodemerck, P. Ignaszewski, M. Lucas, P. Claus, M. Baerns
Single Flow Electrochemical Microreactor Application to Furan Methoxylation 294
R. Ferrigno, V. Reid, H.H. Girault
Part 5
Microfluidics
Lecture Session
Microfluidic Devices for Sample Preparation (Liquid) in the Nanoliter Range 302
H. Fiehn
Liquid Handling in the Pico- and Nanoliter Range 312
W. Meyer, M. Dring
Flow-Through Microdispenser for Liquid Handling in a Levitated-Droplet Based Analyzing System 320
J. Nilsson, T. Laurell, M. Petersson, S. Santesson, T. Johansson, E. Degerman, S. Nilsson
Simulation of Microscale Chemical Separation Processes Using the Lattice-Boltzmann Method 327
D.R. Rector, B.J. Palmer
Modelling of Complex Reaction-Separation Processes in a D.C. Electric Field in Microchannels 336
D. Snita, J. Kosek, H. Sevcikova, J. Lindner, J. Havlica, M. Paces, M. Marek
Poster Session
Microporous Silica Structures for the Immobilisation of Catalysts and Enhancement of Electroosmotic Flow (EOF) in Micro-Reactors 346
N.G. Wilson, T. McCreedy
A New Hydraulic Stroke Amplifier for Microfluidic Components 353
N. Schwesinger, S. Pobering
Part 6
Microreactors for Energy Generation and Storage
Lecture Session
Microchannel Chemical Reactors for Fuel Processing Applications. II. Compact Fuel Vaporization 364
A.L. Y. Tonkovich, S.P. Fitzgerald, J. L. Zilka, M. J. LaMont, Y. Wang, D. P. VanderWiel, R.S. Wegeng
Microstructured Catalysts for Methanol-Steam Reforming 372
P. Pfeifer, M. Fichtner, K. Schubert, M.A. Liauw, G. Emig
Fuel Cells for Low Power Applications 383
C. Hebling, A. Heinzel, D. Golombowski, T. Meyer, M. Mller, M. Zedda
Poster Session
Recent Developments in Microtechnology-Based Chemical Heat Pumps 394
M. K. Drost, M. Friedrich, C. Martin, J. Martin, R.J. Cameron
Miniaturised Direct Methanol Fuel Cell with a Plasma Polymerised Electrolyte Membrane 402
L. Mex, J. Mller
Part 7
Application of Microreactors in Drug Development and Biotechnology
Lecture Session
Rapid PCR in Flow-Through Si Chip Thermocyclers 410
S. Poser, R. Ehricht, T. Schulz, S. Uebel, U. Dillner, J. M. Khler
Disposable Electrophoresis Chip for High Throughput Analysis of Biomolecules 420
R. Konrad, W. Ehrfeld, H.-J. Hartmann, P. Jacob, M. Neumann, R. Pommersheim, I. Sommer, J. Wolfrum
A Micromachined Analysis System for Rapid Protein Identification 430
S. Ekstrm, P. nnerfjord, M. Bengtsson, J. Nilsson, T. Laurell,
G. Marko-Varga
Simulation of Biochemical Reaction Kinetics in Microfluidic Systems 441
V.B. Makhijani, J. Raghavan, A. Przekwas, A.J. Przekwas
Microfluidic Devices on Polymer Substrates for Bioanalytical Applications 451
Y. Lin, D. W. Matson, D.E. Kurath, J. Wen, F. Xiang, W.D. Bennett, P.M. Martin, R.D. Smith
Poster Session
Transfer of Plasmid DNA into Cells with Microelectroporation Arrays on a Chip 461
On-line Monitoring of Enzyme Activities Using Microreactor Heat Power Meters 469
J. Lerchner, A. Wolf, A. Weber, R. Httl, G. Wolf, J.M. Khler, M. Zieren
Isothermal Biochemical Amplification in Miniaturized Reactors with Integrated Microvalves 479
R. Brutigam, D. Steen, R. Ehricht, J.S. McCaskill
Microfluidic Filtration Chip for DNA Extraction and Concentration 488
A. Przekwas, D. Wang, V.B. Makhijani, A.J. Przekwas
Part 8
Commercialization of Microreaction Technology
Lecture Session
The Commercial Use of Multilayer Microcapsules for Biotechnological Applications 500
R. Pommersheim, A. Noack, S. Scholz
Part 9
Microreaction Devices
Lecture Session
A Capillary Force Filled Auto-Mixing Device 506
R.U. Seidel, D.Y. Sim, W. Menz, M. Esashi
Fast Heating and Cooling for High Temperature Chemical Microreactors 514
Ch. Alpe, R. Maurer, L. Paratte, L. Vulpescu, Ph. Renaud, A. Renken
Gas / Liquid Microreactors for Direct Fluorination of Aromatic Compounds Using Elemental Fluorine 526
V. Hesse1, W. Ehrfeld, K. Golbig, V. Haverkamp, H. Lwe, M. Storz, Ch. Wille, A.E. Guber, K. Jhnisch, M. Baerns
Solvent Extraction and Gas Absorption Using Microchannel Contactors 541
W.E. TeGrotenhuis, R.J. Cameron, V. V. Viswanathan, R.S. Wegeng
Poster Session
Polymer Membranes for Product Enrichment in Microreaction Technology 550
B. Schiewe, A. Vuin, N. Giinther, K. Gebauer, Th. Richter, G. Wegner
Compact Heat Exchangers 556
L.A. Luo, U. D'Ortona, D. Tondeur
Optimizing the Geometry of a Catalytic Enzyme Microreactor in Porous Silicon 566
M. Bengtsson, J. Drott, T. Laurell
High Aspect Ratio Silicon Micromachined Heat Exchanger 573
J. Bengtsson, L. Wallman, T. Laurell


Comparison of Two Microvalve Designs Fabricated in Mild Steel 578
B.K. Paul, T. Terhaar
Integrated Microfluidics / Electrochemical Sensor System for Field-Monitoring of Toxic Metals 588
Y. Lin, D.W. Matson, W.D. Bennett, K.D. Thrall, C. Timchalk
Thermoelectrical Measurement System for Chemical Instrumentation 597
S. Beiner, T. Elbel, J.M. Khler, M. Zieren
Electrically Heated Microstructure Heat Exchangers and Reactors 607
J. Brandner, M. Fichtner, K. Schubert
Analytical Module for In-line IR Spectroscopy of Chemical Reactions in Microchannels 617
A.E. Guber, W. Bacher
A Microstructure Reactor for Gas Purification 625
R. Wunsch, M. Fichtner, K. Schubert
A Flexible Multi-Component Microreaction System for Liquid Phase Reactions 636
Th. Richter, W. Ehrfeld, V. Hessel, H. Lwe, M. Storz, A. Wolf
Fast Response Heating Module for Temperature Programmed GC Analysis in Microreaction Systems 645
J. Schiewe, W. Ehrfeld, T. Hang, H. Lwe, Th. Richter, X.L. Yan, A.A. Kurganov, K.K. Unger
A Silicon-based Microreaction System for Analytical Applications 654
P. Woias, K. Hauser, E. Yacoub-George, B. Hillerich
Designing and Constructing Microplants 664
H. Fink, M.J. Hampe
A Modular Microreactor Design for High-Temperature Catalytic Oxidation Reactions 674
G. Veser, G. Friedrich, M. Freygang, R. Zengerle
Microstructured Reactor for Consecutive Heterogeneous / Homogeneous Gas Phase Reactions 687
Th. Richter, W. Ehrfeld, D. Erntner, K. Gebauer, K. Golbig, H. Lwe, A. Lange de Oliveira, W. Schmidt, F. Schth
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