ISBN: 3-540-66760-1
TITLE: The Skin and Gene Therapy
AUTHOR: Hengge, Ulrich; Volc-Platzer, Beatrix (Eds.)
TOC:

Basic Aspects
1 The Epidermal Barrier and Strategies for Surmounting It: An Overview
G.K. Menon, P.M. Elias 3
2 Stem Cells, Differentiation and Renewal Kinetics of Keratinocytes: Implications for Cutaneous Gene Therapy
J.R. Bickenbach 27
3 Relevant Animal Models for Skin Gene Therapy
M.J. Arin, T. Cao, T.R. Berton, Z. Zhou, X.-J. Wang, D.R. Roop 35
4 Nonviral Gene Transfer into the Skin
B. Volc-Platzer, U.R. Hengge, A. Udvardi 53
5 Safety and Pharmacokinetics of Naked Plasmid DNA: Studies on Dissemination and Ectopic Expression
U.R. Hengge, B. Dexling, A. Udvardi, B. Volc-Platzer, A. Mirmohammdsadegh 67
6 Uptake of DNA by Keratinocytes
U.R. Hengge, E. Tschakarjan, A. Mirmohammdsadegh, M. Goos, H.E. Meyer 81
Treatment of Skin Diseases
7 Gene Therapy of Inherited Skin Diseases
G. Meneguzzi, J. Vailly 97
8 Gene Transfer Strategies in Tissue Repair
S.A. Eming, J.M. Davidson, T. Krieg 117
Systemic Effects of Skin Gene Therapy
9 The Use of Skin-Directed Gene Therapy in the Treatment of Systemic Diseases
T.G. Jensen, K.G. Csaky 141
10 Keratinocyte Gene Therapy Using Cytokine Genes
D. Sawamura 155
Genetic Vaccination Using the Skin
11 Principles of Genetic Immunization
D.J. Lee, K. Takabayashi, M. Corr, E. Raz 177
12 Systematic Modulation of Immune Responses by CpG DNA
A.M. Krieg 201
13 Genetic and Dendritic Cell Vaccination as a Novel Therapy for Melanoma
D. Schadendorf, A. Paschen, Y. Sun 219
14 Molecular Strategies Interfering with Tumor Progression of Melanoma and Improving Anti-Tumor Immunity
A. Schneeberger, M. Goos, G. Stingl, S.N. Wagner 245
15 Prophylactic and Therapeutic DNA Vaccines Against Infectious Diseases
J.E. Kallman, H.C. Maguire Jr, J.S. Yang, J.J. Kim,
D.B. Weiner 275
Subject Index 295
END
