## Chapter 9/Figure 2.jpg Back | Home | Next | (A) Distribution of non-cholinergic neurons projecting to the medial prefrontal cortex (light) and the border region between M1 and M2 region (dark). Note the substantial overlap of light and dark cells in the rostral (right hand side of the model) basal forebrain. Fluoro-Gold was injected into two sites in the prefrontal cortex and Fast Blue into the border of the M1/M2 regions (upper left insets). (B) Distribution of cholinergic neurons projecting to the somatosensory (light) and the M1/M2 association region (dark). Note the apparent minimal overlap between the light and dark symbols in the basal forebrain. (C) Overlap analysis from selected sections of case shown in (A). (D) Overlap analysis from the case depicted in (B). For (C) and (D) each section was subdivided into 500 x 500 x 50 micron voxels and the number of cells from each of the two populations (populations '1' and populations '2') was counted in each voxel. Unit spaces containing at least 3 cells of either population are marked with light gray and dark gray, respectively; those containing at least three of both marker types are marked in white. Note the substantial overlap in (C), as indicated by the white voxels. In (D), no white bins are detected indicating no overlap in this case. Note that the gray scalings (colors in the companion CD-ROM file) of the voxels here represents population '1' and/or population '2' and does not correspond to the coding in (A) and (B). The corpus callosum is rendered by double gray/white surfaces around the cingulum bundle in the 3D models.