Chapter 9/Figure 2.jpg
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(A)
Distribution of non-cholinergic neurons projecting to the medial prefrontal
cortex (light) and the border region between M1 and M2 region (dark). Note
the substantial overlap of light and dark cells in the rostral (right hand
side of the model) basal forebrain. Fluoro-Gold was injected into two sites
in the prefrontal cortex and Fast Blue into the border of the M1/M2 regions
(upper left insets). (B) Distribution of cholinergic neurons projecting
to the somatosensory (light) and the M1/M2 association region (dark). Note
the apparent minimal overlap between the light and dark symbols in the basal
forebrain. (C) Overlap analysis from selected sections of case shown in
(A). (D) Overlap analysis from the case depicted in (B). For (C) and (D)
each section was subdivided into 500 x 500 x 50 micron voxels and the number
of cells from each of the two populations (populations '1' and populations
'2') was counted in each voxel. Unit spaces containing at least 3 cells
of either population are marked with light gray and dark gray, respectively;
those containing at least three of both marker types are marked in white.
Note the substantial overlap in (C), as indicated by the white voxels. In
(D), no white bins are detected indicating no overlap in this case. Note
that the gray scalings (colors in the companion CD-ROM file) of the voxels
here represents population '1' and/or population '2' and does not correspond
to the coding in (A) and (B). The corpus callosum is rendered by double
gray/white surfaces around the cingulum bundle in the 3D models. |
